Szukaj
Wyświetlanie pozycji 1-10 z 12
Vitamin B12 and a metal–organic framework enable the photocatalytic generation of alkyl radicals
(Royal Society of Chemistry, 2023)
A versatile Co-catalyst-vitamin B12 (cobalamin)-can be photochemically reduced to its catalytically active Co(I) formunder visible light irradiation, in the presence of MIL-125-NH2(Ti) as a photocatalyst and utilized for ...
Aryl versus Alkyl Redox-Active Diazoacetates ─ Light-Induced C–H Insertion or 1,2-Rearrangement
(American Chemical Society, 2023)
Diazo compounds with redox-active leaving groups are versatile reagents for orthogonal functionalizations, previously utilized in the Rh-catalyzed synthesis of highly substituted cyclopropanes. Photochemical activation of ...
Porphyrins as Promising Photocatalysts for Red-Light-Induced Functionalizations of Biomolecules
(American Chemical Society, 2022)
Red-light enables deeper material penetration, which is important for biological applications and has consequences for chemical synthesis. Therefore, the search for new photocatalysts that absorb in this region is crucial. ...
UV Light Is No Longer Required for the Photoactivation of 1,3,4- Oxadiazolines
(American Chemical Society, 2023)
Carbenes play a key role in a plethora of organic transformations. Although stabilized diazo carbonyl compounds predominate as a source of electrophilic carbenes, the hazardous nature of nonstabilized analogues calls for ...
Pyridine N-oxides as HAT reagents for photochemical C–H functionalization of electron-deficient heteroarenes
(Royal Society of Chemistry, 2022)
Pyridine N-oxides have only recently marked their presence in the photocatalysis field, mainly serving as oxypyridinium salt precursors. Herein, their unique reactivity as a hydrogen atom transfer reagent in photochemical, ...
Effect of amide protoporphyrin derivatives on immune response in Apis mellifera
(Springer Nature, 2022)
The intracellular microsporidian parasite Nosema ceranae is known to compromise bee health by induction of energetic stress and downregulation of the immune system. Porphyrins are candidate therapeutic agents for controlling ...
C−C Bond Forming Reactions Enabled by Vitamin B12 - Opportunities and Challenges
(American Chemical Society, 2022)
Cobalt not only is an essential micronutrient for mammals but also marks itself as important in organic synthesis, especially in the field of catalysis. Various useful reactions, such as alkene hydroformylation, hydrogenation, ...
Site-Selective, Photocatalytic Vinylogous Amidation of Enones
(American Chemical Society, 2022)
Despite the broad interest in organic compounds possessing a γ-aminocarbonyl motif, limited strategies for their synthesis have been reported. Herein, we describe a mild and efficient method for the site-selective amidation ...
Bioinspired Cobalt-Catalysis Enables Generation of Nucleophilic Radicals from Oxetanes
(American Chemical Society, 2022-03-25)
Oxetanes are valuable building blocks due to their well-explored propensity to undergo ring-opening reactions with nucleophiles. However, their application as precursors of radical
species is still elusive. Herein, we ...
C−H Functionalization of Heterocycles with Triplet Carbenes by means of an Unexpected 1,2-Alkyl Radical Migration
(Wiley, 2023)
The C−H functionalization of indole heterocycles constitutes a key strategy to leverage the synthesis of endogenous signaling molecules such as tryptamine or tryptophol. Herein, we report on the photocatalytic reaction of ...