Now showing items 1-20 of 106

    • All-Polymer Microcavities for the Fluorescence Radiative Rate Modification of a Diketopyrrolopyrrole Derivative 

      Megahd, Heba; Lova, Paola; Sardar, Samim; D'Andrea, Cosimo; Lanfranchi, Andrea; Koszarna, Beata; Patrini, Maddalena; Gryko, Daniel T.; Comoretto, Davide (American Chemical Society, 2022)
      Controlling the radiative rate of emitters with macromolecular photonic structures promises flexible devices with enhanced performances that are easy to scale up. For instance, radiative rate enhancement empowers low-threshold ...
    • Analogy of the Reactions of Aromatic and Aliphatic π-Electrophiles with Nucleophiles 

      Barbasiewicz, Michał; Fedoryński, Michał; Loska, Rafał; Mąkosza, Mieczysław (MDPI, 2023)
      The aim of this essay is to disclose the similarity of a great variety of reactions that proceed between nucleophiles and pi-electrophiles—both aromatic and aliphatic. These reactions proceed via initial reversible addition, ...
    • Anion Recognition by a Pincer-Type Host Constructed from Two Polyamide Macrocyclic Frameworks Jointed by a Photo-Addressable Azobenzene Switch 

      Niedbała, Patryk; Ceborska, Magdalena; Mart, Mehmet; Ignacak, Wiktor; Jurczak, Janusz; Dąbrowa, Kajetan (MDPI, 2022)
      A sterically crowded light-responsive host 1 was synthetized with a 93% yield by applying a post-functionalization protocol utilizing the double amidation of 4,4′-azodibenzoyl dichloride with a readily available 26-membered ...
    • Anion-Based Self-assembly of Resorcin[4]arenes and Pyrogallol[4]arenes 

      Chwastek, Monika; Cmoch, Piotr; Szumna, Agnieszka (American Chemical Society, 2022)
      Spatial sequestration of molecules is a prerequisite for the complexity of biological systems, enabling the occurrence of numerous, often non-compatible chemical reactions and processes in one cell at the same time. Inspired ...
    • Aromaticity: Quo Vadis 

      Merino, Gabriel; Solà, Miquel; Fernández, Israel; Foroutan-Nejad, Cina; Lazzeretti, Paolo; Frenking, Gernot; Anderson, Harry L.; Sundholm, Dage; Cossío, Fernando P.; Petrukhina, Marina A.; Wu, Jishan; Wu, Judy I.; Restrepo, Albeiro (Royal Society of Chemistry, 2023)
      Aromaticity is one of the most deeply rooted concepts in chemistry. But why, if two-thirds of existing compounds can be classified as aromatic, is there no consensus on what aromaticity is? σ−, π−, δ−, spherical, Möbius, ...
    • Aryl versus Alkyl Redox-Active Diazoacetates ─ Light-Induced C–H Insertion or 1,2-Rearrangement 

      Santiago, João V.; Orłowska, Katarzyna; Ociepa, Michał; Gryko, Dorota (American Chemical Society, 2023)
      Diazo compounds with redox-active leaving groups are versatile reagents for orthogonal functionalizations, previously utilized in the Rh-catalyzed synthesis of highly substituted cyclopropanes. Photochemical activation of ...
    • Bioinspired Cobalt-Catalysis Enables Generation of Nucleophilic Radicals from Oxetanes 

      Potrząsaj, Aleksandra; Ociepa, Michał; Chaładaj, Wojciech; Gryko, Dorota (American Chemical Society, 2022-03-25)
      Oxetanes are valuable building blocks due to their well-explored propensity to undergo ring-opening reactions with nucleophiles. However, their application as precursors of radical species is still elusive. Herein, we ...
    • Biomimetic Fe–Cu Prophyrrole Aerogel Electrocatalyst for Oxygen Reduction Reaction 

      Persky, Yeela; Kielesiński, Łukasz; Reddy, Samala Nagaprasad; Zion, Noam; Friedman, Ariel; Honig, Hilah C.; Koszarna, Beata; Zachman, Michael J.; Grinberg, Ilya; Gryko, Daniel T.; Elbaz, Lior (American Chemical Society, 2023)
      The development of bioinspired catalysts for oxygen reduction reaction is one of the most prominent pathways in the search for active materials to replace Pt-based catalysts in fuel cells. Herein, we report innovative ...
    • Carboxylated Pillar[5]arene Meets Medicinal Biguanides: Host–Guest Complexes with Alexidine and Phenformin in the Crystal and Solution/Gas Phase 

      Butkiewicz, Helena; Kosiorek, Sandra; Sashuk, Volodymyr; Zimnicka, Magdalena M.; Danylyuk, Oksana (American Chemical Society, 2023)
      Here, we discuss crystal and solution/gas-phase complexes of carboxylated pillar[5]arene with two cationic guests, alexidine and phenformin, revealing host–guest and assembly curiosities, the role of hydrogen bonding, and ...
    • Carboxylated Pillar[6]arene Emulates Pillar[5]arene in the Host–Guest Crystal Complexes and Shows Conformational Flexibility in the Solution/Gas Phase 

      Butkiewicz, Helena; Kosiorek, Sandra; Sashuk, Volodymyr; Zimnicka, Magdalena M.; Danylyuk, Oksana (American Chemical Society, 2023)
      Despite the thriving interest in the aqueous complexation properties of carboxylated pillar[6]arene, its solid state supramolecular chemistry has remained a mystery. Here, overcoming challenging crystallogenesis, we report ...
    • Cascade Transformation of the Ansamycin Benzoquinone Core into Benzoxazole Influencing Anticancer Activity and Selectivity 

      Skrzypczak, Natalia; Pyta, Krystian; Bohusz, Wiktor; Leśniewska, Aleksandra; Gdaniec, Maria; Ruszkowski, Piotr; Schilf, Wojciech; Bartl, Franz; Przybylski, Piotr (American Chemical Society, 2023)
      The metal-free cascade transformation of geldanamycin benzoquinone core is proposed at relatively mild conditions. This approach yields new benzoxazole ansamycin antibiotics and enables their functionalization in an ...
    • Changes in the mitochondrial membrane potential in endothelial cells can be detected by Raman microscopy 

      Pieczara, Anna; Matuszyk, Ewelina; Szcześniak, Piotr; Młynarski, Jacek; Barańska, Małgorzata (Elsevier, 2022)
      The role of mitochondria goes beyond their capacity to create molecular fuel and includes e.g. the production of reactive oxygen species and the regulation of cell death. In endothelial cells, mitochondria have a significant ...
    • Chiral Water-Soluble Molecular Capsules With Amphiphilic Interiors 

      Sakowicz, Arkadiusz Marek; Szumna, Agnieszka (Frontiers Media, 2022-04-14)
      We present the synthesis of new chiral water-soluble dimeric capsules by the multicomponent Mannich reaction between charged amino acids (glutamic acid or arginine), resorcinarene, and formaldehyde and by subsequent ...
    • Collective interactions among organometallics are exotic bonds hidden on lab shelves 

      Sowlati-Hashjin, Shahin; Šadek, Vojtěch; Abdolreza Sadjadi, Seyed; Karttunen, Mikko; Martín-Pendás, Angel; Foroutan-Nejad, Cina (Springer Nature, 2022-04-19)
      Recent discovery of an unusual bond between Na and B in NaBH3− motivated us to look for potentially similar bonds, which remained unnoticed among systems isoelectronic with NaBH3−. Here, we report a novel family of collective ...
    • A computer algorithm to discover iterative sequences of organic reactions 

      Molga, Karol; Szymkuć, Sara; Gołębiowska, Patrycja; Popik, Oskar; Dittwald, Piotr; Moskal, Martyna; Roszak, Rafał; Młynarski, Jacek; Grzybowski, Bartosz A. (Springer Nature, 2022)
      Iterative syntheses comprise sequences of organic reactions in which the substrate molecules grow with each iteration and the functional groups, which enable the growth step, are regenerated to allow sustained cycling. ...
    • Computer-designed repurposing of chemical wastes into drugs 

      Wołos, Agnieszka; Koszelewski, Dominik; Roszak, Rafał; Szymkuć, Sara; Moskal, Martyna; Ostaszewski, Ryszard; Brezicki, Gordon; Samuel, Jonathon; McQuade, D. Tyler; Rogers, Luke; Grzybowski, Bartosz A.; Herrera, Brenden T.; Maier, Josef M.; Lummiss, Justin A. M. (Nature, 2022-04-27)
      As the chemical industry continues to produce considerable quantities of waste chemicals1,2, it is essential to devise ‘circular chemistry’3,4,5,6,7,8 schemes to productively back-convert at least a portion of these unwanted ...
    • Conformation of the Ester Group Governs the Photophysics of Highly Polarized Benzo[g]coumarins 

      Szychta, Kamil; Koszarna, Beata; Banasiewicz, Marzena; Sobolewski, Andrzej; O’Mari, Omar; Clark, John A.; Vullev, Valentine I.; Barboza, Cristina A.; Gryko, Daniel T. (American Chemical Society, 2023)
      Photosensitizers that display “unusual” emission from upper electronically excited states offer possibilities for initiating higher-energy processes than what the governing Kasha’s rule postulates. Achieving conditions for ...
    • Conversion of Ketones into Blue-Emitting Electron-Deficient Benzofurans 

      Górski, Krzysztof; Ostojić, Tea; Banasiewicz, Marzena; Ouellette, Erik T.; Grisanti, Luca; Gryko, Daniel T. (Wiley, 2023)
      A novel heavy metal-free and safe synthetic methodology enabling one-step conversion of ketones into corresponding 4,5,6,7-tetrafluorobenzofurans (F4BFs) has been developed. The presented approach has numerous advantageous ...
    • Copolymers Containing 1-Methyl-2-phenyl-imidazole Moieties as Permanent Dipole Generating Units: Synthesis, Spectroscopic, Electrochemical, and Photovoltaic Properties 

      Kulszewicz-Bajer, Irena; Nowakowski, Robert; Zagórska, Małgorzata; Maranda-Niedbała, Agnieszka; Mech, Wojciech; Wróbel, Zbigniew; Drapała, Jakub; Wielgus, Ireneusz; Korona, Krzysztof P. (MDPI, 2022)
      New donor–acceptor conjugated alternating or random copolymers containing 1-methyl-2- phenylbenzimidazole and benzothiadiazole (P1), diketopyrrolopyrrole (P4), or both acceptors (P2) are reported. The specific feature of ...
    • C−C Bond Forming Reactions Enabled by Vitamin B12 - Opportunities and Challenges 

      Wdowik, Tomasz; Gryko, Dorota (American Chemical Society, 2022)
      Cobalt not only is an essential micronutrient for mammals but also marks itself as important in organic synthesis, especially in the field of catalysis. Various useful reactions, such as alkene hydroformylation, hydrogenation, ...