Bioinspired Cobalt-Catalysis Enables Generation of Nucleophilic Radicals from Oxetanes
Date
2022-03-25Author
Potrząsaj, Aleksandra
Ociepa, Michał
Chaładaj, Wojciech
Gryko, Dorota
Metadata
Show full item recordAbstract
Oxetanes are valuable building blocks due to their well-explored propensity to undergo ring-opening reactions with nucleophiles. However, their application as precursors of radical
species is still elusive. Herein, we present a bioinspired cobalt catalysis-based strategy to access unprecedented modes of radical
reactivity via oxetane ring-opening. This powerful approach gives access to nucleophilic radicals that engage in reactions with SOMOphiles and low-valent transition metals. Importantly, the regioselectivity of these processes complements known methodologies.
Collections
- Artykuły IChO PAN [112]
The following license files are associated with this item: