Epigenetic regulation of the proliferation in breast tumours
Zaporozhan, V. M.
Romak, R. P.
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Abstract The study was aimed was to compare the activity of gene methylation GSHR in patients with breast cancer and patients with fibro- cystic mastopathy. There was demonstrated that mean activity GSHR gene methylation in patients with breast cancer is significantly higher than in patients with FKM (respectively 51,6 ± 2,5% and 4,9 ± 1,2%. Determined confidence intervals for the parameter methylation activity suggest that when it values above 24.9% can not exclude the development of malignant tumors of the breast.
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