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Wyświetlanie pozycji 11-15 z 15
Computer-designed repurposing of chemical wastes into drugs
(Nature, 2022-04-27)
As the chemical industry continues to produce considerable quantities of waste chemicals1,2, it is essential to devise ‘circular chemistry’3,4,5,6,7,8 schemes to productively back-convert at least a portion of these unwanted ...
Intensification of Double Kinetic Resolution of Chiral Amines and Alcohols via Chemoselective Formation of a Carbonate–Enzyme Intermediate
(MDPI, 2022)
Chiral amines and alcohols are synthons of numerous pharmaceutically-relevant compounds. The previously developed enzymatic kinetic resolution approaches utilize a chiral racemic molecule and achiral acyl donor (or acyl ...
Influence of Open Chain and Cyclic Structure of Peptidomimetics on Antibacterial Activity in E. coli Strains
(MDPI, 2022)
An efficient method for the synthesis of functionalized peptidomimetics via multicomponent Ugi reaction has been developed. The application of trifluoroethanol (TFE) as a reaction medium provided desired products with good ...
Enzymatic Synthesis of a Novel Coumarin Aminophosphonates: Antibacterial Effects and Oxidative Stress Modulation on Selected E. coli Strains
(MDPI, 2023)
The objective of the present study was to evaluate the synergistic effect of two important pharmacophores, coumarin and -amino dimethyl phosphonate moieties, on antimicrobial activity toward selected LPS-varied E. coli ...
Interdisciplinary approach to synthesis, stability and antimicrobial activity of silver nanoparticles
(Termedia sp. z o.o., 2023)
Chronic wounds are an increasing problem for health care all over the world. New treatment options for this illness are desired, especially antimicrobial agents. Silver nanoparticles (AgNPs) can be a potential substance ...